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Peter Schönfeld Selected Research

Phytanic Acid

3/2016Brain Lipotoxicity of Phytanic Acid and Very Long-chain Fatty Acids. Harmful Cellular/Mitochondrial Activities in Refsum Disease and X-Linked Adrenoleukodystrophy.
7/2006A study of the cytotoxicity of branched-chain phytanic acid with mitochondria and rat brain astrocytes.
4/2006Mechanism of toxicity of the branched-chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment.
3/2006Rotenone-like action of the branched-chain phytanic acid induces oxidative stress in mitochondria.
2/2005The Refsum disease marker phytanic acid, a branched chain fatty acid, affects Ca2+ homeostasis and mitochondria, and reduces cell viability in rat hippocampal astrocytes.
10/2004In brain mitochondria the branched-chain fatty acid phytanic acid impairs energy transduction and sensitizes for permeability transition.
1/2004Phytanic Acid toxicity: implications for the permeability of the inner mitochondrial membrane to ions.

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Peter Schönfeld Research Topics

Disease

7Refsum Disease (Refsum's Disease)
03/2016 - 01/2004
3Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
03/2016 - 06/2008
3Peroxisomal Disorders (Peroxisomal Disorder)
04/2006 - 01/2004
2Inborn Genetic Diseases (Disease, Hereditary)
03/2016 - 10/2004
2Neurodegenerative Diseases (Neurodegenerative Disease)
03/2016 - 05/2015
2Neoplasms (Cancer)
08/2013 - 02/2005
1Brain Injuries (Brain Injury)
01/2021
1Body Weight (Weight, Body)
03/2020
1Insulin Resistance
03/2020
1Gallstones (Gallstone)
03/2020
1Ulcerative Colitis
12/2013
1Hypoxia (Hypoxemia)
07/2011
1Nervous System Heredodegenerative Disorders
06/2008
1Parkinson Disease (Parkinson's Disease)
03/2006
1Dehydration (Water Stress)
09/2005
1Colonic Neoplasms (Colon Cancer)
02/2005

Drug/Important Bio-Agent (IBA)

7Phytanic AcidIBA
03/2016 - 01/2004
7Fatty Acids (Saturated Fatty Acids)IBA
03/2016 - 02/2005
2Member 1 Subfamily D ATP Binding Cassette TransporterIBA
03/2016 - 05/2015
2Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
12/2013 - 08/2013
1Phospholipids (Phosphatides)FDA LinkGeneric
01/2021
1Glucagon-Like Peptide 1 (GLP 1)IBA
03/2020
1CholesterolIBA
03/2020
1Detergents (Detergent)IBA
03/2020
1Carrier Proteins (Binding Protein)IBA
05/2015
1Complementary DNA (cDNA)IBA
08/2013
1Nonesterified Fatty Acids (NEFA)IBA
07/2011
1Reactive Oxygen Species (Oxygen Radicals)IBA
07/2011
1Oxygen (Dioxygen)IBA
07/2011
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
07/2011
1Pramipexole (Mirapex)FDA LinkGeneric
03/2006
1Neuroprotective AgentsIBA
03/2006
1thiocyanateIBA
09/2005
1DNA Methyltransferase 3AIBA
02/2005
1ChlorophyllIBA
02/2005
1MethyltransferasesIBA
02/2005

Therapy/Procedure

1Gastric Bypass (Roux-en-Y Gastric Bypass)
03/2020
1Bariatric Surgery
03/2020
1Therapeutics
08/2013